The HER2 status was as follows: negative in 751 cases, 1+ in 440 cases, 2+ in 123 cases, and 3+ in 238 cases. The PPV and NPV describe the performance of a diagnostic test or other statistical measure. ... Clearly, this is a prognostic as well as predictive indicator. Positive inguinal nodes and positive margins were identified as prognostic factors either for overall survival and disease specific survival; tumor size greater than 4 cm was identified as prognostic factors for overall survival. The lymph node ratio as an independent prognostic factor for node-positive triple-negative breast cancer. They are also more likely to come back after treatment. For lymph node-negative patients, only tumor size and grade were significant prognostic factors. Moreover, TOP2A was independently associated with DMFS in the HR+/HER2− subtype. Methods: Clinical characteristics of patients were collected from the Surveillance, Epidemiology, and End Results (SEER) database. Pathological characteristics and clinical records of 841 TNBCs diagnosed between 1994 and 2015 in four major oncologic centers from Sardinia, Italy, were reviewed. These results demonstrated that the expression of MMP11 and CD2 are independent prognostic factors for HR−/HER2+ breast cancer. Prognostic factors specific to each entity have not been adequately explored. 53(3):598-604. Only N0 versus N1–3 classification was significant. Of the more traditional prognostic factors related to Prognostic factor defined as measurement taken at time of diagnosis or treatment that is associated with outcome. Prognostic factors of node-negative large tumours. Abstract. Clinical and pathological factors influencing survival in a large cohort of triple-negative … Abstract 4166Background:. in lymph node-negative patients was 33.0 months, and in lymph node- positive patients, it was 19.0 months. 2017; 8: 44870-80, CrossRef. The relationship of other prognostic factors with positive peritoneal cytology remains unclear. HER2-positive breast cancer is more aggressive and more likely to spread than HER2-negative breast cancer. Prognostic factors include those characteristics that will define the natural history of the disease, and predictive factors are those that will tell us whether a particular therapeutic intervention will result in a favorable outcome. Background: Negative lymph node (NLN) count has been reported to associate with the prognosis of various cancers. Prognostic factors in node‐positive carcinoma of the penis Prognostic factors in node‐positive carcinoma of the penis Pandey, Durgatosh; Mahajan, Vikash; Kannan, R. Ravi 2006-02-01 00:00:00 Background: Lymph node metastasis is the most important prognostic factor in patients with carcinoma of the penis. Prognostic factors for systemic relapses and for … To provide further information on the clinical and pathological prognostic factors in triple-negative breast cancer (TNBC), for which limited and inconsistent data are available. Neurology . Purpose: To analyze prognostic and predictive effects of immunohistochemical factors within a randomized study of high-dose versus standard-dose chemotherapy in high-risk breast cancer with >10 involved lymph nodes. To conclude, this study identified discontinuation of whole-brain radiotherapy and presence of triple-negative breast cancer as poor prognostic factors. The prognostic significance of positive peritoneal cytology in patients with early-stage endometrial cancer (Stage 1 or 2) is controversial and perhaps depends on the presence of other factors. Conclusions Patient and methods. In this article, we have reviewed the outcome of the patients with pathologic … Urru SAM, Gallus S, Bosetti C, Moi T, Medda R, Sollai E, et al. BACKGROUND: The objective of this study was to evaluate prognostic factors of local and distant recurrence in patients diagnosed with T1a and T1b, lymph node‐negative breast carcinoma (BC) with emphasis on human epidermal growth factor receptor 2 (HER2) status. We conducted a retrospective analysis to examine the clinical characteristics and prognostic factors in HIV-negative and HIV-positive patients with PCNSL and to assess the effect of highly active antiretroviral therapy (HAART) therapy on the outcome of HIV-positive patients. The purpose of this study was to assess the recurrence patterns and prognostic factors in LVSI-positive patients with pure endometrioid EC who have undergone systematic LN dissection and found to have negative LNs. Therefore, we conducted this retrospective, dual-institutional study in order to shed some more light on these issues. A prognostic factor may be defined as a measurable variable … Dutch Guillain-Barré Study Group. both positive and negative control sections were in-cluded for each antibody. The X-tile program was used to determine the optimal cutoffs for NLN count. Age at diagnosis No prognostic differences between the patients with N1, N2 or N3 disease subtypes (p=0.78) were detected. positive disease to warrant adjuvant systemic therapy since, generally, a future risk of distant recurrence of 20% or greater is regarded significant enough to consider the risks of therapy. None of the shape, margin or orientation characteristics was associated with the prognostic factors. Oncotarget. EBV-positive diffuse large B-cell lymphoma (DLBCL) of the elderly is an entity recently described and included in the WHO cl Several factors have been associated with a better overall prognosis: Being female, rapid (vs. insidious) onset of symptoms, older age of first episode, predominantly positive (rather than negative) symptoms, presence of mood symptoms, and good pre-illness functioning. HIV-positive patients were younger, more likely to present with seizures and elevated serum LDH levels. Once the diagnosis had been confirmed, several prognostic factors were analyzed: 1) Nuclear atypia, following the method reported by Spangler and Kass,20 using an incremental scale from 1 to 10, signifying the subjectively estimated percentage of nuclei involved; 2) After intravenous immunoglobulin or plasma exchange phrases related to cancer and medicine size and were. Prognosis of various cancers well as predictive indicator C, Moi T, Medda R Sollai. 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